Circulating Chromogranin A Is Cleaved Into Vasoregulatory Fragments in Patients With Pancreatic Ductal Adenocarcinoma

Chromogranin A (CgA), a secretory protein released in the blood by the neuroendocrine system, consists of a mixture of full-length molecules and fragments endowed of vasoregulatory activity. The extent and the role of CgA fragmentation were investigated in patients with locally advanced or metastati...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Reni, Michele, Andreasi, Valentina, Gasparri, Anna Maria, Dugnani, Erica, Colombo, Barbara, Macchini, Marina, Bianco, Mimma, Dallatomasina, Alice, Citro, Antonio, Assi, Emma, Protti, Maria Pia, Esposito, Antonio, Falconi, Massimo, Curnis, Flavio, Piemonti, Lorenzo, Corti, Angelo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787052/
https://ncbi.nlm.nih.gov/pubmed/33425767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.613582
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