Randomized phase II study comparing the efficacy and safety of SOX versus mFOLFOX6 as neoadjuvant chemotherapy without radiotherapy for locally advanced rectal cancer (KSCC1301)

BACKGROUND: Preoperative chemoradiotherapy (CRT), the current standard of care for locally advanced rectal cancer (LARC), is associated with many radiotherapy (RT)-related side effects. We aimed to evaluate whether S-1 and oxaliplatin (SOX) or folinic acid, 5-FU, and oxaliplatin (mFOLFOX6) can be as...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Miwa, Keisuke, Oki, Eiji, Enomoto, Masanobu, Ihara, Keisuke, Ando, Koji, Fujita, Fumihiko, Tominaga, Masahiro, Mori, Shinichiro, Nakayama, Goro, Shimokawa, Mototsugu, Saeki, Hiroshi, Baba, Hideo, Mori, Masaki, Akagi, Yoshito
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786922/
https://ncbi.nlm.nih.gov/pubmed/33402130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07766-5
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