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Signal Transduction Profiling of Angiotensin II Type 1 Receptor With Mutations Associated to Atrial Fibrillation in Humans

The AT1 receptor (AT1R) has a major role in the Renin-Angiotensin System, being involved in several physiological events including blood pressure control and electrolyte balance. The AT1R is a member of the G protein coupled receptors (GPCR) family, classically known to couple G(αq) and engage β-arr...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Simões, Sarah C., Balico-Silva, André L., Parreiras-e-Silva, Lucas T., Bitencourt, André L. B., Bouvier, Michel, Costa-Neto, Claudio M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786401/
https://ncbi.nlm.nih.gov/pubmed/33424609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.600132
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