Reversal of Age-Related Neuronal Atrophy by α5-GABAA Receptor Positive Allosteric Modulation

Aging is associated with reduced brain volume, altered neural activity, and neuronal atrophy in cortical-like structures, comprising the frontal cortex and hippocampus, together contributing to cognitive impairments. Therapeutic efforts aimed at reversing these deficits have focused on excitatory or...

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Publicat a:Cereb Cortex
Autors principals: Prevot, Thomas D, Sumitomo, Akiko, Tomoda, Toshifumi, Knutson, Daniel E, Li, Guanguan, Mondal, Prithu, Banasr, Mounira, Cook, James M, Sibille, Etienne
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786363/
https://ncbi.nlm.nih.gov/pubmed/33068001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhaa310
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