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Expeditious Generation of Biparatopic Common Light Chain Antibodies via Chicken Immunization and Yeast Display Screening

Bispecific (BsAb) and biparatopic (BpAb) antibodies emerged as promising formats for therapeutic biologics exhibiting tailor-made functional properties. Over recent years, chicken-derived antibodies have gained traction for diagnostic and therapeutic applications due to their broad epitope coverage...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bogen, Jan P., Carrara, Stefania C., Fiebig, David, Grzeschik, Julius, Hock, Björn, Kolmar, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786285/
https://ncbi.nlm.nih.gov/pubmed/33424853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.606878
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