LncRNA DHRS4-AS1 Inhibits the Stemness of NSCLC Cells by Sponging miR-224-3p and Upregulating TP53 and TET1

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death. This study aimed to examine the roles of DHRS4-AS1/miR-224-3p signaling in the cancer cell stemness of NSCLC. Real-time PCR showed that DHRS4-AS1 was downregulated in cancerous tissues, and bioinformatics analysis revea...

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Опубликовано в: :Front Cell Dev Biol
Главные авторы: Yan, Fei, Zhao, Wei, Xu, Xiaoyue, Li, Chenchen, Li, Xiaoyou, Liu, Siwen, Shi, Lin, Wu, Yuan
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Cell and Developmental Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786137/
https://ncbi.nlm.nih.gov/pubmed/33425890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.585251
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