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qPCR and qRT-PCR analysis: Regulatory points to consider when conducting biodistribution and vector shedding studies

Gene and cell therapy fields have experienced remarkable growth during the past decade. Demands for preclinical and clinical safety assessments of these cell and gene therapy test articles (TAs) have effectively increased the necessity for regulated biodistribution, vector shedding, gene expression,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Methods Clin Dev
Hauptverfasser: Ma, Haiyan, Bell, Kristin N., Loker, Rossi N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786041/
https://ncbi.nlm.nih.gov/pubmed/33473355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.11.007
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