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Improved HLA-based prediction of coeliac disease identifies two novel genetic interactions
Human Leucocyte Antigen (HLA) testing is useful in the clinical work-up of coeliac disease (CD) with high negative but low positive predictive value. We construct a genomic risk score (GRS) using HLA risk genotypes to improve CD prediction and guide exclusion criteria. Imputed HLA genotypes for five...
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| Gepubliceerd in: | Eur J Hum Genet |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Springer International Publishing
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7785002/ https://ncbi.nlm.nih.gov/pubmed/32733071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-020-0700-2 |
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