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Unique combination and in silico modeling of biallelic POLR3A variants as a cause of Wiedemann–Rautenstrauch syndrome

Neonatal progeroid syndrome or Wiedemann–Rautenstrauch syndrome (WRS; MIM 264090) is a rare genetic disorder that has clinical symptoms including premature aging, lipodystrophy, and variable mental impairment. Until recently genetic background of the disease was unclear. However, recent studies have...

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Detalles Bibliográficos
Publicado en:Eur J Hum Genet
Main Authors: Temel, Sehime Gulsun, Ergoren, Mahmut Cerkez, Manara, Elena, Paolacci, Stefano, Tuncel, Gulten, Gul, Seref, Bertelli, Matteo
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784914/
https://ncbi.nlm.nih.gov/pubmed/32555393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-020-0673-1
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