Blood–Brain Barrier Leakage Is Increased in Parkinson’s Disease

BACKGROUND: Blood–brain barrier (BBB) disruption has been noted in animal models of Parkinson’s disease (PD) and forms the basis of the vascular hypothesis of neurodegeneration, yet clinical studies are lacking. OBJECTIVE: To determine alterations in BBB integrity in PD, with comparison to cerebrova...

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Udgivet i:Front Physiol
Main Authors: Al-Bachari, Sarah, Naish, Josephine H., Parker, Geoff J. M., Emsley, Hedley C. A., Parkes, Laura M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784911/
https://ncbi.nlm.nih.gov/pubmed/33414722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.593026
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