Increased expression of hypoxia-induced factor 1α mRNA and its related genes in myeloid blood cells from critically ill COVID-19 patients

BACKGROUND: COVID-19 counts 46 million people infected and killed more than 1.2 million. Hypoxaemia is one of the main clinical manifestations, especially in severe cases. HIF1α is a master transcription factor involved in the cellular response to oxygen levels. The immunopathogenesis of this severe...

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Udgivet i:Ann Med
Main Authors: Taniguchi-Ponciano, Keiko, Vadillo, Eduardo, Mayani, Héctor, Gonzalez-Bonilla, César Raúl, Torres, Javier, Majluf, Abraham, Flores-Padilla, Guillermo, Wacher-Rodarte, Niels, Galan, Juan Carlos, Ferat-Osorio, Eduardo, Blanco-Favela, Francisco, Lopez-Macias, Constantino, Ferreira-Hermosillo, Aldo, Ramirez-Renteria, Claudia, Peña-Martínez, Eduardo, Silva-Román, Gloria, Vela-Patiño, Sandra, Mata-Lozano, Carlos, Carvente-Garcia, Roberto, Basurto-Acevedo, Lourdes, Saucedo, Renata, Piña-Sanchez, Patricia, Chavez-Gonzalez, Antonieta, Marrero-Rodríguez, Daniel, Mercado, Moisés
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784832/
https://ncbi.nlm.nih.gov/pubmed/33345622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07853890.2020.1858234
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