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Structural insight into the novel iron‐coordination and domain interactions of transferrin‐1 from a model insect, Manduca sexta

Transferrins function in iron sequestration and iron transport by binding iron tightly and reversibly. Vertebrate transferrins coordinate iron through interactions with two tyrosines, an aspartate, a histidine, and a carbonate anion, and conformational changes that occur upon iron binding and releas...

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Vydáno v:Protein Sci
Hlavní autoři: Weber, Jacob J., Kashipathy, Maithri M., Battaile, Kevin P., Go, Eden, Desaire, Heather, Kanost, Michael R., Lovell, Scott, Gorman, Maureen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784759/
https://ncbi.nlm.nih.gov/pubmed/33197096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3999
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