Aplastic anemia in a patient with CVID due to NFKB1 haploinsufficiency

Acquired aplastic anemia (AA) is a life-threatening bone marrow failure caused by an autoimmune cytotoxic T lymphocyte attack on hematopoietic stem and progenitor cells. Factors contributing to aberrant autoimmune activation in AA include a deficit of T regulatory cells and high levels of inflammato...

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Bibliographic Details
Published in:Cold Spring Harb Mol Case Stud
Main Authors: Sklarz, Tammarah, Hurwitz, Stephanie N., Stanley, Natasha L., Juusola, Jane, Bagg, Adam, Babushok, Daria
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2020
Subjects:
Research Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784489/
https://ncbi.nlm.nih.gov/pubmed/32972988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a005769
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