Siglec-E retards atherosclerosis by inhibiting CD36-mediated foam cell formation

BACKGROUND: The accumulation of lipid-laden macrophages, foam cells, within sub-endothelial intima is a key feature of early atherosclerosis. Siglec-E, a mouse orthologue of human Siglec-9, is a sialic acid binding lectin predominantly expressed on the surface of myeloid cells to transduce inhibitor...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biomed Sci
Main Authors: Hsu, Yaw-Wen, Hsu, Fu-Fei, Chiang, Ming-Tsai, Tsai, Dong-Lin, Li, Fu-An, Angata, Takashi, Crocker, Paul R., Chau, Lee-Young
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784283/
https://ncbi.nlm.nih.gov/pubmed/33397354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-020-00698-z
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