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Effects of α(1)-adrenergic receptor antagonists on the development and progression of urothelial cancer

We recently demonstrated that silodosin, a selective α(1)-blocker often prescribed for the symptomatic treatment of benign prostatic hyperplasia (BPH), could inactivate a c-fos proto-oncogene regulator ELK1 in bladder cancer cells possessing a functional androgen receptor (AR). However, the clinical...

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Pubblicato in:Am J Cancer Res
Autori principali: Nagata, Yujiro, Kawahara, Takashi, Goto, Takuro, Inoue, Satoshi, Teramoto, Yuki, Jiang, Guiyang, Fujimoto, Naohiro, Miyamoto, Hiroshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783756/
https://ncbi.nlm.nih.gov/pubmed/33415006
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