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Immunology of IL-12: An update on functional activities and implications for disease

As its first identified member, Interleukin-12 (IL-12) named a whole family of cytokines. In response to pathogens, the heterodimeric protein, consisting of the two subunits p35 and p40, is secreted by phagocytic cells. Binding of IL-12 to the IL-12 receptor (IL-12R) on T and natural killer (NK) cel...

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Dades bibliogràfiques
Publicat a:EXCLI J
Autors principals: Ullrich, Karen A.-M., Schulze, Lisa Lou, Paap, Eva-Maria, Müller, Tanja M., Neurath, Markus F., Zundler, Sebastian
Format: Artigo
Idioma:Inglês
Publicat: Leibniz Research Centre for Working Environment and Human Factors 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783470/
https://ncbi.nlm.nih.gov/pubmed/33408595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2020-3104
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