A Novel Gene Delivery Vector of Agonistic Anti-Radioprotective 105 Expressed on Cell Membranes Shows Adjuvant Effect for DNA Immunization Against Influenza

Radioprotective 105 (RP105) (also termed CD180) is an orphan and unconventional Toll-like receptor (TLR) that lacks an intracellular signaling domain. The agonistic anti-RP105 monoclonal antibody (mAb) can cross-link RP105 on B cells, resulting in the proliferation and activation of B cells. Anti-RP...

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Vydáno v:Front Immunol
Hlavní autoři: Yamazaki, Tatsuya, Biswas, Mrityunjoy, Kosugi, Kouyu, Nagashima, Maria, Inui, Masanori, Tomono, Susumu, Takagi, Hidekazu, Ichimonji, Isao, Nagaoka, Fumiaki, Ainai, Akira, Hasegawa, Hideki, Chiba, Joe, Akashi-Takamura, Sachiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783388/
https://ncbi.nlm.nih.gov/pubmed/33414788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.606518
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