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Heme as Possible Contributing Factor in the Evolvement of Shiga-Toxin Escherichia coli Induced Hemolytic-Uremic Syndrome

Shiga-toxin (Stx)-producing Escherichia coli hemolytic-uremic syndrome (STEC-HUS) is one of the most common causes of acute kidney injury in children. Stx-mediated endothelial injury initiates the cascade leading to thrombotic microangiopathy (TMA), still the exact pathogenesis remains elusive. Inte...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Wijnsma, Kioa L., Veissi, Susan T., de Wijs, Sem, van der Velden, Thea, Volokhina, Elena B., Wagener, Frank A. D. T. G., van de Kar, Nicole. C. A. J., van den Heuvel, L. P.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783363/
https://ncbi.nlm.nih.gov/pubmed/33414780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.547406
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