Evaluation of neurobiological and antioxidant effects of novel melatonin analogs in mice

Based on the pharmacophore model of melatonin (MT(1)) receptor, we recently synthesized a series of indole derivatives that showed anticonvulsant activity with low neurotoxicity and hepatotoxicity in rodents. In the present study, the three most potent C3-modified derivatives with hydrazine structur...

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Veröffentlicht in:Saudi Pharm J
Hauptverfasser: Tchekalarova, Jana, Ivanova, Natasha, Nenchovska, Zlatina, Tzoneva, Rumiana, Stoyanova, Tzveta, Uzunova, Veselina, Surcheva, Slavina, Tzonev, Alex, T. Angelova, Violina, Andreeva-Gateva, Pavlina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783092/
https://ncbi.nlm.nih.gov/pubmed/33424250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2020.10.004
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