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Integrated molecular characterisation of the MAPK pathways in human cancers reveals pharmacologically vulnerable mutations and gene dependencies

The mitogen-activated protein kinase (MAPK) pathways are crucial regulators of the cellular processes that fuel the malignant transformation of normal cells. The molecular aberrations which lead to cancer involve mutations in, and transcription variations of, various MAPK pathway genes. Here, we exa...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Commun Biol
मुख्य लेखकों: Sinkala, Musalula, Nkhoma, Panji, Mulder, Nicola, Martin, Darren Patrick
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782843/
https://ncbi.nlm.nih.gov/pubmed/33398072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01552-6
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