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MCM3 upregulation confers endocrine resistance in breast cancer and is a predictive marker of diminished tamoxifen benefit
Resistance to endocrine therapy in estrogen receptor-positive (ER(+)) breast cancer is a major clinical problem with poorly understood mechanisms. There is an unmet need for prognostic and predictive biomarkers to allow appropriate therapeutic targeting. We evaluated the mechanism by which minichrom...
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| Publicado no: | NPJ Breast Cancer |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7782683/ https://ncbi.nlm.nih.gov/pubmed/33398005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-020-00210-8 |
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