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A human surfactant B deficiency air-liquid interface cell culture model suitable for gene therapy applications
Surfactant protein B (SPB) deficiency is a severe monogenic interstitial lung disorder that leads to loss of life in infants as a result of alveolar collapse and respiratory distress syndrome. The development and assessment of curative therapies for the deficiency are limited by the general lack of...
Gespeichert in:
| Veröffentlicht in: | Mol Ther Methods Clin Dev |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Gene & Cell Therapy
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7782204/ https://ncbi.nlm.nih.gov/pubmed/33426150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.11.013 |
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