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Synthesis, telomerase inhibitory and anticancer activity of new 2-phenyl-4H-chromone derivatives containing 1,3,4-oxadiazole moiety

Based on previous studies, 66 2-phenyl-4H-chromone derivatives containing amide and 1,3,4-oxadiazole moieties were prepared as potential telomerase inhibitors. The results showed most of the title compounds exhibited significantly inhibitory activity on telomerase. Among them, some compounds demonst...

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Foilsithe in:J Enzyme Inhib Med Chem
Main Authors: Han, Xu, Yu, Yun Long, Ma, Duo, Zhang, Zhao Yan, Liu, Xin Hua
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782168/
https://ncbi.nlm.nih.gov/pubmed/33356666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1864630
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