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Anti-GD2 antibody and Vorinostat immunocombination therapy is highly effective in an aggressive orthotopic neuroblastoma model

Neuroblastoma is a childhood malignancy and in the majority of patients, the primary tumor arises in one of the adrenal glands. Neuroblastoma cells highly express the disialoganglioside GD2, which is the primary target for the development of neuroblastoma immunotherapy. Anti-GD2 mAbs have shown clin...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: van den Bijgaart, Renske J. E., Kroesen, Michiel, Brok, Ingrid C., Reijnen, Daphne, Wassink, Melissa, Boon, Louis, Hoogerbrugge, Peter M., Adema, Gosse J
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781842/
https://ncbi.nlm.nih.gov/pubmed/33457098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1817653
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