The average copy number variation (CNVA) of chromosome fragments is a potential surrogate for tumor mutational burden in predicting responses to immunotherapy in non‐small‐cell lung cancer

OBJECTIVES: The tumor mutational burden (TMB) is closely related to immunotherapy outcome. However, the cost of TMB detection is extremely high, which limits its use in clinical practice. A new indicator of genomic instability, the average copy number variation (CNVA), calculates the changes of 0.5‐...

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Publicat a:Clin Transl Immunology
Autors principals: Lei, Yuanyuan, Zhang, Guochao, Zhang, Chaoqi, Xue, Liyan, Yang, Zhenlin, Lu, Zhiliang, Huang, Jianbing, Zang, Ruochuan, Che, Yun, Mao, Shuangshuang, Fang, Lingling, Liu, Chengming, Wang, Xinfeng, Zheng, Sufei, Sun, Nan, He, Jie
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781741/
https://ncbi.nlm.nih.gov/pubmed/33425353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1231
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