P53 induces senescence in the unstable progeny of aneuploid cells

Aneuploidy is the condition of having an imbalanced karyotype, which is associated with tumor initiation, evolution, and acquisition of drug-resistant features, possibly by generating heterogeneous populations of cells with distinct genotypes and phenotypes. Multicellular eukaryotes have therefore e...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Giam, Maybelline, Wong, Cheng Kit, Low, Jun Siong, Sinelli, Matteo, Dreesen, Oliver, Rancati, Giulia
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781663/
https://ncbi.nlm.nih.gov/pubmed/33305692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2020.1850968
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