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Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest

Different subsets of the tRNA pool in human cells are expressed in different cellular conditions. The ‘proliferation-tRNAs’ are induced upon normal and cancerous cell division, while the ‘differentiation-tRNAs’ are active in non-dividing, differentiated cells. Here we examine the essentiality of the...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Aharon-Hefetz, Noa, Frumkin, Idan, Mayshar, Yoav, Dahan, Orna, Pilpel, Yitzhak, Rak, Roni
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781600/
https://ncbi.nlm.nih.gov/pubmed/33357381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58461
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