Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

The continual emergence of novel coronavirus (CoV) strains, like SARS-CoV-2, highlights the critical need for broadly reactive therapeutics and vaccines against this family of viruses. Coronavirus spike (S) proteins share common structural motifs that could be vulnerable to cross-reactive antibody r...

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Publicado no:bioRxiv
Main Authors: Shiakolas, Andrea R., Kramer, Kevin J., Wrapp, Daniel, Richardson, Simone I., Schäfer, Alexandra, Wall, Steven, Wang, Nianshuang, Janowska, Katarzyna, Pilewski, Kelsey A., Venkat, Rohit, Parks, Rob, Manamela, Nelia P., Raju, Nagarajan, Fechter, Emilee Friedman, Holt, Clinton M., Suryadevara, Naveenchandra, Chen, Rita E., Martinez, David R., Nargi, Rachel S., Sutton, Rachel E., Ledgerwood, Julie E., Graham, Barney S., Diamond, Michael S., Haynes, Barton F., Acharya, Priyamvada, Carnahan, Robert H., Crowe, James E., Baric, Ralph S., Morris, Lynn, McLellan, Jason S., Georgiev, Ivelin S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781301/
https://ncbi.nlm.nih.gov/pubmed/33398266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.12.20.414748
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