Urinary Leukotriene E(4) and Prostaglandin D(2) Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study

Rationale: New approaches are needed to guide personalized treatment of asthma. Objectives: To test if urinary eicosanoid metabolites can direct asthma phenotyping. Methods: Urinary metabolites of prostaglandins (PGs), cysteinyl leukotrienes (CysLTs), and isoprostanes were quantified in the U-BIOPRE...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Am J Respir Crit Care Med
المؤلفون الرئيسيون: Kolmert, Johan, Gómez, Cristina, Balgoma, David, Sjödin, Marcus, Bood, Johan, Konradsen, Jon R., Ericsson, Magnus, Thörngren, John-Olof, James, Anna, Mikus, Maria, Sousa, Ana R., Riley, John H., Bates, Stewart, Bakke, Per S., Pandis, Ioannis, Caruso, Massimo, Chanez, Pascal, Fowler, Stephen J., Geiser, Thomas, Howarth, Peter, Horváth, Ildikó, Krug, Norbert, Montuschi, Paolo, Sanak, Marek, Behndig, Annelie, Shaw, Dominick E., Knowles, Richard G., Holweg, Cécile T. J., Wheelock, Åsa M., Dahlén, Barbro, Nordlund, Björn, Alving, Kjell, Hedlin, Gunilla, Chung, Kian Fan, Adcock, Ian M., Sterk, Peter J., Djukanovic, Ratko, Dahlén, Sven-Erik
التنسيق: Artigo
اللغة:Inglês
منشور في: American Thoracic Society 2021
الموضوعات:
Original Articles
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781128/
https://ncbi.nlm.nih.gov/pubmed/32667261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201909-1869OC
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