Urinary Leukotriene E(4) and Prostaglandin D(2) Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study

Rationale: New approaches are needed to guide personalized treatment of asthma. Objectives: To test if urinary eicosanoid metabolites can direct asthma phenotyping. Methods: Urinary metabolites of prostaglandins (PGs), cysteinyl leukotrienes (CysLTs), and isoprostanes were quantified in the U-BIOPRE...

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Bibliografiset tiedot
Julkaisussa:Am J Respir Crit Care Med
Päätekijät: Kolmert, Johan, Gómez, Cristina, Balgoma, David, Sjödin, Marcus, Bood, Johan, Konradsen, Jon R., Ericsson, Magnus, Thörngren, John-Olof, James, Anna, Mikus, Maria, Sousa, Ana R., Riley, John H., Bates, Stewart, Bakke, Per S., Pandis, Ioannis, Caruso, Massimo, Chanez, Pascal, Fowler, Stephen J., Geiser, Thomas, Howarth, Peter, Horváth, Ildikó, Krug, Norbert, Montuschi, Paolo, Sanak, Marek, Behndig, Annelie, Shaw, Dominick E., Knowles, Richard G., Holweg, Cécile T. J., Wheelock, Åsa M., Dahlén, Barbro, Nordlund, Björn, Alving, Kjell, Hedlin, Gunilla, Chung, Kian Fan, Adcock, Ian M., Sterk, Peter J., Djukanovic, Ratko, Dahlén, Sven-Erik
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Thoracic Society 2021
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Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781128/
https://ncbi.nlm.nih.gov/pubmed/32667261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201909-1869OC
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