Neutrophil Extracellular Traps Increase Airway Mucus Viscoelasticity and Slow Mucus Particle Transit

Mucus obstruction is a key feature of many inflammatory airway diseases. Neutrophil extracellular traps (NETs) are released upon neutrophil stimulation and consist of extracellular chromatin networks studded with cytotoxic proteins. When released in the airways, these NETs can become part of the air...

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Veröffentlicht in:Am J Respir Cell Mol Biol
Hauptverfasser: Linssen, Rosalie S., Chai, Guihong, Ma, Jonathan, Kummarapurugu, Apparao B., van Woensel, Job B. M., Bem, Reinout A., Kaler, Logan, Duncan, Gregg A., Zhou, Lei, Rubin, Bruce K., Xu, Qingguo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2021
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780998/
https://ncbi.nlm.nih.gov/pubmed/33095650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2020-0168OC
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