Tanshinone IIA Ameliorates Streptozotocin-Induced Diabetic Nephropathy, Partly by Attenuating PERK Pathway-Induced Fibrosis

PURPOSE: Tanshinone IIA (Tan IIA), a compound extracted from Salvia miltiorrhiza, can improve type II diabetes, while the molecular mechanisms underlying Tan IIA-mediated protective effects in diabetic nephropathy are unclear. This study explored the protective actions of Tan IIA on renal tissues in...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Xu, Shujuan, He, Lianjun, Ding, Keke, Zhang, Lingling, Xu, Xinhui, Wang, Sheng, Qian, Xueyi
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780857/
https://ncbi.nlm.nih.gov/pubmed/33408464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S257734
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