Experimental and theoretical rationalization for the base pairing abilities of inosine, guanosine, adenosine, and their corresponding 8‐oxo‐7,8‐dihydropurine, and 8‐bromopurine analogues within A‐form duplexes of RNA

Inosine is an important RNA modification, furthermore RNA oxidation has gained interest due, in part, to its potential role in the development/progression of disease as well as on its impact on RNA structure and function. In this report we established the base pairing abilities of purine nucleobases...

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Veröffentlicht in:Biopolymers
Hauptverfasser: Skinner, Austin, Yang, Chou‐Hsun, Hincks, Kazuki, Wang, Haobin, Resendiz, Marino J. E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780609/
https://ncbi.nlm.nih.gov/pubmed/33216981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.23410
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