PGC‐1α is downregulated in a mouse model of obstructive cholestasis but not in a model of liver fibrosis

Several studies have indicated that cholestatic liver damage involves mitochondria dysfunction. However, the precise mechanism by which hydrophobic bile salts cause mitochondrial dysfunction is not clear. In this study, we intended to determine the pathogenesis of cholestatic liver injury associated...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Park, Jung Hyun, Kwak, Bong Jun, Choi, Ho Joong, Kim, Ok‐Hee, Hong, Ha‐Eun, Lee, Sang Chul, Kim, Kee‐Hwan, You, Young Kyoung, Lee, Tae Yun, Ahn, Joseph, Kim, Say‐June
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780111/
https://ncbi.nlm.nih.gov/pubmed/32860664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12961
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