Spatiotemporal immunolocalisation of REST in the brain of healthy ageing and Alzheimer’s disease rats

In the brain, REST (Repressor Element‐1 Silencing Transcription factor) is a key regulator of neuron cell‐specific gene expression. Nuclear translocation of neuronal REST has been shown to be neuroprotective in a healthy ageing context. In contrast, inability to upregulate nuclear REST is thought to...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Mampay, Myrthe, Velasco‐Estevez, María, Rolle, Sara O., Chaney, Aisling M., Boutin, Hervé, Dev, Kumlesh K., Moeendarbary, Emad, Sheridan, Graham K.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780110/
https://ncbi.nlm.nih.gov/pubmed/33185010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13036
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