Spatiotemporal immunolocalisation of REST in the brain of healthy ageing and Alzheimer’s disease rats

In the brain, REST (Repressor Element‐1 Silencing Transcription factor) is a key regulator of neuron cell‐specific gene expression. Nuclear translocation of neuronal REST has been shown to be neuroprotective in a healthy ageing context. In contrast, inability to upregulate nuclear REST is thought to...

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Vydáno v:FEBS Open Bio
Hlavní autoři: Mampay, Myrthe, Velasco‐Estevez, María, Rolle, Sara O., Chaney, Aisling M., Boutin, Hervé, Dev, Kumlesh K., Moeendarbary, Emad, Sheridan, Graham K.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780110/
https://ncbi.nlm.nih.gov/pubmed/33185010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13036
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