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The Development of Integrin Alpha-8 Deficient Lungs Shows Reduced and Altered Branching and a Correction of the Phenotype During Alveolarization

Lung development involves epithelial–mesenchymal interactions and integrins represent one of the key elements. These extracellular matrix receptors form hetero-dimers of alpha and beta subunits. The integrin α8β1 is highly expressed in mouse tissues, including lung. It forms a cellular receptor for...

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Bibliografski detalji
Izdano u:Front Physiol
Glavni autori: Cremona, Tiziana P., Hartner, Andrea, Schittny, Johannes C.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779808/
https://ncbi.nlm.nih.gov/pubmed/33408636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.530635
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