Scaling parameter of the lethal effect of mammalian cells based on radiation-induced OH radicals: effectiveness of direct action in radiation therapy

We have been studying the effectiveness of direct action, which induces clustered DNA damage leading to cell killing, relative to indirect action. Here a new criterion Direct Ation-Based Biological Effectiveness (DABBLE) is proposed to understand the contribution of direct action for cell killing in...

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Detalhes bibliográficos
Publicado no:J Radiat Res
Main Authors: Kusumoto, Tamon, Ogawara, Ryo, Igawa, Kazuyo, Baba, Kentaro, Konishi, Teruaki, Furusawa, Yoshiya, Kodaira, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Technical Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779345/
https://ncbi.nlm.nih.gov/pubmed/33313873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rraa111
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