Hepatitis B virus P protein initiates glycolytic bypass in HBV-related hepatocellular carcinoma via a FOXO3/miRNA-30b-5p/MINPP1 axis

BACKGROUND: Hepatitis B virus (HBV) infection is a crucial risk factor for hepatocellular carcinoma (HCC). However, its underlying mechanism remains understudied. METHODS: Microarray analysis was conducted to compare the genes and miRNAs in liver tissue from HBV-positive and HBV-negative HCC patient...

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Udgivet i:J Exp Clin Cancer Res
Main Authors: Chen, Wenbiao, Jiang, Jingjing, Gong, Lan, Shu, Zheyue, Xiang, Dairong, Zhang, Xujun, Bi, Kefan, Diao, Hongyan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779247/
https://ncbi.nlm.nih.gov/pubmed/33390177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01803-8
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