Peptides derived from small mitochondrial open reading frames: Genomic, biological, and therapeutic implications

Mitochondrial-derived peptides (MDPs) are a novel class of bioactive microproteins that modify cell metabolism. The the eight MDPs that been characterized (e.g., humanin, MOTS-c, SHLPs1-6) attenuate disease pathology including Alzheimer’s disease, prostate cancer, macular degeneration, cardiovascula...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Exp Cell Res
Main Authors: Miller, Brendan, Kim, Su-Jeong, Kumagai, Hiroshi, Mehta, Hemal H., Xiang, Wang, Liu, Jiali, Yen, Kelvin, Cohen, Pinchas
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7778388/
https://ncbi.nlm.nih.gov/pubmed/32387288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2020.112056
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