Cotrimoxazole Prophylaxis Increases Resistance Gene Prevalence and α-Diversity but Decreases β-Diversity in the Gut Microbiome of Human Immunodeficiency Virus–Exposed, Uninfected Infants

BACKGROUND: Prophylactic cotrimoxazole treatment is recommended in human immunodeficiency virus (HIV)–exposed, uninfected (HEU) infants, but the effects of this treatment on developing HEU infant gut microbiotas and resistomes are largely undefined. METHODS: We analyzed whole-metagenome sequencing d...

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Publicado en:Clin Infect Dis
Main Authors: D’Souza, Alaric W, Moodley-Govender, Eshia, Berla, Bertram, Kelkar, Tejas, Wang, Bin, Sun, Xiaoqing, Daniels, Brodie, Coutsoudis, Anna, Trehan, Indi, Dantas, Gautam
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
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Major Articles and Commentaries
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7778358/
https://ncbi.nlm.nih.gov/pubmed/31832638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciz1186
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