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1190. Dual-Plasmid Technology for Precision Genome Editing in Staphylococcus aureus

BACKGROUND: Genetic manipulation of Staphylococcus aureus (both methicillin sensitive S. aureus, MSSA, and methicillin resistant S. aureus, MRSA) poses a technical challenge due to poor transformation efficiency, limited endogenous DNA repair activity, lineage-specific methylation patterns and intri...

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Bibliografiske detaljer
Udgivet i:Open Forum Infect Dis
Main Authors: Reish, Jennifer, Dey, Somrita, Penewit, Kelsi, Salipante, Stephen J, Berti, Andrew David
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7777601/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofaa439.1375
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