1207. Combining standard bacterial vaginosis treatment with cystine uptake inhibitors to block growth of Lactobacillus iners is a potential a target for shifting the cervicovaginal microbiota towards health-associated Lactobacillus crispatus-dominant communities

BACKGROUND: Cervicovaginal microbiota domination by Lactobacillus crispatus is associated with beneficial health outcomes, whereas L. iners dominance has more adverse associations. However bacterial vaginosis (BV) treatment with metronidazole (MTZ) typically leads to domination by L. iners rather th...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Bloom, Seth M, Mafunda, Nomfuneko A, Woolston, Benjamin M, Hayward, Matthew R, Frempong, Josephine F, Xu, Jiawu, Mitchell, Alissa, Westergaard, Xavier, Rice, Justin K, Choksi, Namit, Balskus, Emily P, Mitchell, Caroline M, Kwon, Douglas S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Poster Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7777507/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofaa439.1392
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