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De novo ZIC2 frameshift variant associated with frontonasal dysplasia in a Limousin calf

BACKGROUND: Bovine frontonasal dysplasias like arhinencephaly, synophthalmia, cyclopia and anophthalmia are sporadic congenital facial malformations. In this study, computed tomography, necropsy, histopathological examinations and whole genome sequencing on an Illumina NextSeq500 were performed to c...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Braun, Marina, Lehmbecker, Annika, Eikelberg, Deborah, Hellige, Maren, Beineke, Andreas, Metzger, Julia, Distl, Ottmar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7777292/
https://ncbi.nlm.nih.gov/pubmed/33388042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-07350-y
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