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Analysis of retrotransposon subfamily DNA methylation reveals novel early epigenetic changes in chronic lymphocytic leukemia

Retrotransposons such as LINE-1 and Alu comprise >25% of the human genome. While global hypomethylation of these elements has been widely reported in solid tumours, their epigenetic dysregulation is yet to be characterised in chronic lymphocytic leukemia (CLL), and there has been scant considerat...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Barrow, Timothy M., Doo, Nicole Wong, Milne, Roger L., Giles, Graham G., Willmore, Elaine, Strathdee, Gordon, Byun, Hyang-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Fondazione Ferrata Storti 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7776340/
https://ncbi.nlm.nih.gov/pubmed/31919093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.228478
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