1453. PBP2, PBP2a and PBP4 Clone-specific Polymorphisms are not Associated to Ceftaroline (CPT) Susceptibility in Chilean Clinical Isolates of Methicillin-Resistant Staphylococcus aureus (MRSA)

BACKGROUND: CPT is a last-generation cephalosporin active against MRSA due to its affinity for PBP2a. CPT-resistance (CPT-R) is well-described, with mutations in the active transpeptidase domain of PBP2a associated to high-level resistance. The accumulation of changes in the non-penicillin-binding d...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Open Forum Infect Dis
Autori principali: Spencer, Maria de los Angeles, Martinez, José Rodrigo, Rivas, Lina María, rojas, Marcelo, Rios, Rafael, Dinh, An Q, Diaz, Lorena, Reyes, Jinnethe, Hanson, Blake, Garcia, Patricia, Arias, Cesar A, Munita, Jose M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Poster Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7776269/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofaa439.1634
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