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Autoantibody-mediated desialylation impairs human thrombopoiesis and platelet lifespan

Immune thrombocytopenia is a common bleeding disease caused by autoantibody-mediated accelerated platelet clearance and impaired thrombopoiesis. Accumulating evidence suggests that desialylation affects platelet lifespan in immune thrombocytopenia. Herein, we report on novel effector functions of au...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Marini, Irene, Zlamal, Jan, Faul, Christoph, Holzer, Ursula, Hammer, Stefanie, Pelzl, Lisann, Bethge, Wolfgang, Althaus, Karina, Bakchoul, Tamam
Formato: Artigo
Idioma:Inglês
Publicado em: Fondazione Ferrata Storti 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7776251/
https://ncbi.nlm.nih.gov/pubmed/31857361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.236117
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