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A Temporal Quantitative Profiling of Newly Synthesized Proteins during Aβ Accumulation

Accumulation of aggregated amyloid beta (Aβ) in the brain is believed to impair multiple cellular pathways and play a central role in Alzheimer’s disease pathology. But how this process is regulated remains unclear. In theory, measuring protein synthesis is the most direct way to evaluate a cell’s r...

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Detalles Bibliográficos
Publicado en:J Proteome Res
Autores principales: Ma, Yuanhui, McClatchy, Daniel B., Martínez-Bartolomé, Salvador, Bamberger, Casimir, Yates, John R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775911/
https://ncbi.nlm.nih.gov/pubmed/33147027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.0c00645
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