Hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) alters maternal and fetal glucose and lipid metabolism and produces neonatal mortality, low birthweight, and hepatomegaly in the Sprague-Dawley rat

Hexafluoropropylene oxide dimer acid (HFPO-DA or GenX) is an industrial replacement for the straight-chain perfluoroalkyl substance (PFAS), perfluorooctanoic acid (PFOA). Previously we reported maternal, fetal, and postnatal effects from gestation day (GD) 14–18 oral dosing in Sprague-Dawley rats. H...

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Vydáno v:Environ Int
Hlavní autoři: Conley, Justin M., Lambright, Christy S., Evans, Nicola, McCord, James, Strynar, Mark J., Hill, Donna, Medlock-Kakaley, Elizabeth, Wilson, Vickie S., Gray, L. Earl
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775906/
https://ncbi.nlm.nih.gov/pubmed/33126064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.envint.2020.106204
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