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Improved radiosynthesis of (123)I-MAPi, an Auger theranostic agent

PURPOSE: (123)I-MAPi, a novel PARP1-targeted Auger radiotherapeutic has shown promising results in pre-clinical glioma model. Currently (123)I-MAPi is synthesized using multistep synthesis that results in modest yields and low molar activities that limits the ability to translate this technology for...

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Bibliographic Details
Published in:Int J Radiat Biol
Main Authors: Wilson, Thomas C., Jannetti, Stephen A., Guru, Navjot, Pillarsetty, Nagavarakishore, Reiner, Thomas, Pirovano, Giacomo
Format: Artigo
Language:Inglês
Published: 2023
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775866/
https://ncbi.nlm.nih.gov/pubmed/32552309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09553002.2020.1781283
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