Potential natural inhibitors of xanthine oxidase and HMG-CoA reductase in cholesterol regulation: in silico analysis

BACKGROUND: Hypercholesterolemia has posed a serious threat of heart diseases and stroke worldwide. Xanthine oxidase (XO), the rate-limiting enzyme in uric acid biosynthesis, is regarded as the root of reactive oxygen species (ROS) that generate atherosclerosis and cholesterol crystals. β-Hydroxy β-...

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Dettagli Bibliografici
Pubblicato in:BMC Complement Med Ther
Autori principali: Marahatha, Rishab, Basnet, Saroj, Bhattarai, Bibek Raj, Budhathoki, Prakriti, Aryal, Babita, Adhikari, Bikash, Lamichhane, Ganesh, Poudel, Darbin Kumar, Parajuli, Niranjan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775628/
https://ncbi.nlm.nih.gov/pubmed/33386071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-020-03162-5
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