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Role of NDE1 in the Development and Evolution of the Gyrified Cortex

An expanded cortex is a hallmark of human neurodevelopment and endows increased cognitive capabilities. Recent work has shown that the cell cycle-related gene NDE1 is essential for proper cortical development. Patients who have mutations in NDE1 exhibit congenital microcephaly as a primary phenotype...

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Publicat a:Front Neurosci
Autors principals: Soto-Perez, Jaseph, Baumgartner, Marybeth, Kanadia, Rahul N.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775536/
https://ncbi.nlm.nih.gov/pubmed/33390896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.617513
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